團(tuán)隊(duì)人員：

1.         研究組長(zhǎng)：林鑫華研究員，首批國(guó)家“千人計(jì)劃”高層次海外引進(jìn)人才，“973”計(jì)劃首席科學(xué)家。 1984年畢業(yè)于杭州大學(xué)生物系，獲學(xué)士學(xué)位；1987年畢業(yè)于中國(guó)科學(xué)院上海細(xì)胞生物學(xué)研究所，并獲得碩士學(xué)位；1995年畢業(yè)于美國(guó)華盛頓大學(xué)，獲得博士學(xué)位。1995年至2000年在哈佛大學(xué)醫(yī)學(xué)院進(jìn)行博士后研究。2000-2008年受聘于美國(guó)辛辛那提兒童醫(yī)院發(fā)育生物學(xué)系，歷任助理教授、副教授、教授。2008年受聘于溫州醫(yī)科大學(xué)，組建信號(hào)轉(zhuǎn)導(dǎo)與發(fā)育機(jī)理研究組。目前擔(dān)任中國(guó)動(dòng)物學(xué)會(huì)理事、中國(guó)細(xì)胞生物學(xué)會(huì)北京分會(huì)副理事長(zhǎng);任國(guó)際期刊 Developmental Dynamics、Fly、The Open Cell Signaling Journal  編委，擔(dān)任《細(xì)胞生物學(xué)學(xué)報(bào)》副主編。

2.         工作人員：葉曉蕾、馮穎、林益

研究方向

       從多個(gè)重要的信號(hào)通路包括Wg、Hh、TGF-β等出發(fā)，利用果蠅全基因組RNAi文庫(kù)、果蠅全基因組過(guò)表達(dá)文庫(kù)和蛋白質(zhì)組學(xué)等多種手段，篩選 鑒定參與形態(tài)發(fā)生素信號(hào)通路的新基因，研究這些基因在形態(tài)發(fā)生素梯度形成和信號(hào)轉(zhuǎn)導(dǎo)中的功能和機(jī)制，以及對(duì)眼發(fā)育的影響。

Laboratory of signal transduction and development mechanism

Team members

1.         Principal Investigator: Xinhua Lin, PhD

Xinhua Lin is recruited by the "Thousand Talents Plan" and the chief scientist of "973" plan. He graduated from the Department of Biology, Hangzhou University in 1984 with a bachelor's degree and later got his master’s degree from the Shanghai Institute of Cell Biology, Chinese Academy of Sciences in 1987. Then Dr. Lin received his PhD from Washington University in 1995 and completed a postdoctoral training in Harvard Medical School from 1995 to 2000 .From 2000 to 2008, Dr. Lin worked successively as an Assistant Professor, Associate Professor and Full Professor in Cincinnati Children’s Hospital Medical Center. Dr. Lin became the PI of signal transduction and development mechanism research group in Wenzhou Medical University since 2008. Also, he was appointed as the member of editorial board of journal of Development Dynamics and Fly

2.         Team staff: Xiaolei Ye, Ying Feng, Yi Lin

Scope of Research Proposal

1.       Screening and identifying the new genes involved in Wg, Hh and TGF-β and other morphogen related signal transduction pathway.

      2.     Reveal the mechanism and function of these new genes in eye development.